GPCR Conformations: Implications for Rational Drug Design
نویسندگان
چکیده
منابع مشابه
GPCR Conformations: Implications for Rational Drug Design
G protein-coupled receptors (GPCRs) comprise a large class of transmembrane proteins that play critical roles in both normal physiology and pathophysiology. These critical roles offer targets for therapeutic intervention, as exemplified by the substantial fraction of current pharmaceutical agents that target members of this family. Tremendous contributions to our understanding of GPCR structure...
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ژورنال
عنوان ژورنال: Pharmaceuticals
سال: 2010
ISSN: 1424-8247
DOI: 10.3390/ph4010007